Abstract:The levels of serum lipoprotein (a)[Lp(a)], apolipoprotein A1 (Apo A1), apolipoprotein B (Apo B), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), total cholesterol (TC), triglyceride(TG),malondialdehyde ( MDA ) and superoxide dismutase (SOD) were measured in 30 old healthy subjects and 44 old patients with coronary heart disease (CHD).Lp (a), Apo B, LDLC and MDA were higher, and Apo A1, HDLC and SOD were lower in CHD patients than in controls (P<0. 05 or P<0. 01). Multiple regression analysis revealed that levels of LDLC correlated signiflcantly with level of MDA (r=0. 5139,P<0.001 ) and level of HDLC correlated significantly with serum SOD activity (r=0. 5702,P<0. 001). The results suggested that hyperlipemia in old CHD patients was closer relationship to lipids peroxidation.