Aim To investigate the intervenient efficacy of lipid lowing therapy as well as blood pressure controling in carotid arteriosclerosis and stroke of patients with hypertension. Methods The carotid artery colordopler ultrasonography was examed and the levels of serum lipids were measured in 102 cases of hypertension using the Micronised Ferofibrate compared with 105 controls during 24 monthes. Results The intima-media thickness (IMT) of carotid artery was almost unchanged in lipid lowing intervention group after this period of treatment. The IMT/D ratio and the incidence of carotid arteriosclerosis plaque were reduced signifficantly after the therapy.The relative risk of stroke in intervention group was lowered by 34% compared with the controls. Conclusion The carotid arteriosclerosis and the stroke in hypertension could be well prevented with lipid lowing therapy while the patient's blood pressure had been controled.