正常高值血压者颈动脉和股动脉弹性的改变及其相关性
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河北省医学科学研究重点课题计划项目(ZD20140447)


Correlation of Elasticity Change Between Carotid Artery and Femoral Artery in Patients with High-normal Blood Pressure
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    目的 探讨正常高值血压者颈动脉和股动脉弹性的改变及其相关性。方法 用二维超声测量76例正常高值血压者与50例正常对照者双侧颈动脉、股动脉内膜中膜厚度(IMT),并应用超声血管回声跟踪技术检测颈动脉、股动脉弹性参数,即硬度指数(β)、压力应变弹性系数(Ep)、动脉顺应性(AC)及脉搏波传导速度(PWV),并对正常高值血压者颈动脉、股动脉弹性参数进行相关性分析。结果 正常高值血压组颈动脉、股动脉的β、Ep、PWV均较正常对照组增高(P<0.001),AC较正常对照组降低(P<0.001);正常高值血压组颈动脉、股动脉的IMT与正常对照组比较无差异(P>0.05);正常高值血压者颈动脉与股动脉弹性参数β、Ep、PWV的相关系数分别为0.354、0.304、0.360,呈显著正相关(P<0.001),颈动脉IMT、AC与股动脉IMT、AC之间无显著相关性(r=0.108,P=0.184;r=0.114,P=0.163)。结论 正常高值血压者颈动脉、股动脉弹性在动脉内膜中膜未出现超声形态学改变前已经降低,且同步受累。

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    Aim To explore the correlation of elasticity change between carotid artery and femoral artery in patients with high-normal blood pressure. Methods Intima-media thickness (IMT) in the bilateral carotid artery and femoral artery was measured by two-dimensional ultrasound in 76 patients (including male 42 cases and female 34 cases,mean age 47.56±10.54 years old) with high-normal blood pressure and 50 cases of normal control group (including male 26 cases and female 24 cases,mean age 48.16±11.17 years old),carotid artery and femoral artery elastic parameters of β,Ep,arterial compliance (AC) and pulse wave velocity (PWV) were detected by echo tracking technology,and correlation of carotid artery and femoral artery was analyzed. Results Compared with normal control group,β,Ep,PWV of carotid artery and femoral artery were increased conspicuously in high-normal blood pressure group (P<0.001),AC was lower significantly in high-normal blood pressure group (P<0.001).There was no difference in IMT of carotid artery and femoral artery between the two groups respectively (P>0.05).The correlation coefficients of β,Ep,PWV in carotid artery and femoral artery in patients with high-normal blood pressure were 0.354,0.304 and 0.360 (P<0.001),which was a significant positive correlation.There were no significant correlation of IMT and AC between carotid and femoral artery (r=0.108,P=0.184 r=0.114,P=0.163). Conclusion The carotid and femoral artery elasticity decreased and involved simultaneously before the artery IMT had ultrasonic morphological change.

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阚艳敏,马 琳,杨 华,李 劼,孙玉伟.正常高值血压者颈动脉和股动脉弹性的改变及其相关性[J].中国动脉硬化杂志,2015,23(07):685~688.

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  • 收稿日期:2014-10-13
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  • 在线发布日期: 2015-07-03