原发性高血压患者早餐餐后低血压与血压晨峰的相关性
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(聊城市中医医院心内科,山东省聊城市 252000)

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王才进,主治医师,研究方向为心血管疾病的预防保健,E-mail为13806358918@163.com。

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Correlation Between Postprandial Hypotension of Breakfast and Morning Blood Pressure Surge
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Department of Cardiology, the Hospital of Traditional Chinese Medicine of Liaocheng City, Liaocheng, Shandong 252000, China)

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    摘要:

    目的 分析原发性高血压患者早餐餐后低血压(postprandial hypotension,PPH)与血压晨峰的相关性。方法 将行24 h动态血压监测的原发性高血压患者135例分三组,其中仅有原发性高血压组(非PPH组)45例,合并早餐餐后低血压组45例,合并中晚餐餐后低血压组45例,观察三组平均血压、血压负荷值、勺型率、血压变异性及晨峰值等指标。结果 (1)合并早餐餐后低血压组24 h、日间、夜间收缩压变异性及24 h、日间舒张压变异性明显高于非PPH组及合并中晚餐餐后低血压组,且差异有统计学意义(P<0.05)。(2)合并早餐餐后低血压组患者血压晨峰值及晨峰发生率明显高于非PPH组及合并中晚餐餐后低血压组,差异有统计学意义(P<0.05)。(3)餐前血压越高越容易发生餐后低血压,餐前血压与餐后血压下降值成正相关(r=0.548,P<0.001),早餐餐前血压与早餐后血压下降值成正相关(r=0.623,P<0.001)。结论 餐前血压越高越易发生餐后低血压,早餐餐后低血压患者血压变异性增高,更易发生晨峰现象。

    Abstract:

    Aim To analyse correlation between postprandial hypotension(PPH) of breakfast and morning blood pressure surge in essential hypertension patients. Methods 135 patients with essential hypertension who proceed 24 h ambulatory blood pressure were divided into non-PPH group(n=45), and postprandial hypotension of breakfast group(PPH-1 group)(n=45), and postprandial hypotension of lunch and dinner(PPH-2 group)(n=45). Average blood pressure, blood pressure load values, dipper rate, blood pressure variability and morning surge were observed in three groups. Results (1)24hSBPV, 24hDBPV, dSBPV, dDBPV, nSBPV of PPH-1 group was obviously higher than that of the non-PPH and PPH-2 group, and the difference was statistically significant(P<0.05).(2)The morning surge value and morning blood pressure surge ratio of the PPH-1 group was significantly higher than that of non-PPH and PPH-2 group(P<0.05).(3)Preprandial SBP was positively correlated with postprandial fall in SBP after meal(r=0.548,P<0.001).Breakfast preprandial SBP was positively correlated with postprandial fall in SBP after breakfast(r=0.623,P<0.001). Conclusion The higher the preprandial blood pressure, the more prone to PPH, breakfast postprandial hypotension patients have a higher blood pressure variability, morning surge phenomenon happens more easily.

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王才进,何冰,么传为,陈明荣,许宏珂.原发性高血压患者早餐餐后低血压与血压晨峰的相关性[J].中国动脉硬化杂志,2016,24(7):693~697.

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  • 收稿日期:2015-08-25
  • 最后修改日期:2016-01-04
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  • 在线发布日期: 2016-07-05