Calcific aortic valve disease is frequently observed in the elderly. Currently, there is no treatment to reverse established calcific aortic valve disease. The responsible underlying molecular mechanisms have yet to be fully elucidated. Previous studies have demonstrated that calcific aortic valve disease shares many similarities to that of bone formation and bone metabolisms. lncRNAs are defined as non-coding transcripts longer than 200 nucleotides, with important biological functions. Emerging data have shown that lncRNAs differentially express in calcified aortic valves compared to normal control, which contribute significantly to the pathogenesis of calcific aortic valve disease through a number of distinct mechanisms. This study reviews here the current progress of lncRNAs and calcific aortic valve disease in recent years. These studies shed new lights on pathogenic mechanisms of calcific aortic valve disease.