The etiology pathology etc of atherosclerosis (As) have been studied widely for many years. From the traditional medicine viewpoint,the mechanism of stasis exsisted in As. So the Chinese drug recipe of removing stagnancy of vital energy of the liver and invigorating blood circulation was subjucted in treatment of As. From the molecullar level of cytobiology, the effect of Chinese drugs on content of lipid peroxide (LPO) and activity of superoxide dismutase (SOD) were studied in vitro cultured SMC of rabbit aorta. The results showed that content of LPO in SMC were lower in Chinese drugs group than that in the control group (P<0. 01), activity of SOD in SMC were higher in Chinese drugs group than that in the control group (P< 0. 01). This Chinese drug recipe may obviously ruduce the content LPO of SMC, raise the activity of SOD, protect the normal function,metabolism and complete constitution. Thus, the Chinese drug recipe reduce the pathological changes of make it tend to motionless.