Aim To investigate the effects of atorvastatin calcium on plasma homocysteine （Hcy） and carotid artery atherosclerosis in patients with H type hypertension. Methods 180 cases of H type hypertensive patients （50～79 years old） were randomly divided into atorvastatin （10 mg/d） treatment group （n＝92） and conventional treatment group i.e.control group （n＝88）. Blood pressure,blood lipids,Hcy,high-sensitive C-reactive protein （hs-CRP）,and intima-media thickness （IMT） were determined before and after 6 months treatment in all patients. Results In atorvastatin treatment group,after 6 months treatment,the level of low density lipoprotein cholesterol was significantly decreased from 2.69±0.44 mmol/L to 1.95±0.37 mmol/L the level of Hcy was significantly decreased from 15.86±3.37 μmol/L to 9.96±3.35 μmol/L the level of hs-CRP was significantly decreased from 5.88±2.82 mg/L to 3.75±2.37 mg/L the IMT was significantly decreased from 1.97±0.76 mm to 1.47±0.68 mm （all P＜0.05）. No significant change was observed in control group. Conclusion On the basis of conventional antihypertension,atorvastatin can significantly decrease the level of plasma Hcy,inhibit inflammatory reaction,and slow down the formation of atherosclerotic plaque in patients with H type hypertension.