Aim To investigate the influnce of simvastatin on serum LDL oxidation and platelet activation in CAD patients. Methods 38 CAD patients and 38 normal subjects were enrolled. The serum level of ox LDL、 TXB 2 and the levels of alpha granule membrane protein (GMP 140) on the surface of platelet were measured before and after the simvastatin treatment four weeks. The relationship between ox LDL、 GMP 140、 TXB 2 and HDL was analysed. Results The ... 更多