Aim To study how mongolian proprietariesⅡ and proprietariesⅢ function in inhibiting the atheroscleroisis. Methods To make the model of rabbit atheroscleroisis, to detect the content of blood-fat and the lipid peroxide, and to observe aorta and coronal artery with eyes or through light microscope and electric system. Results Each of this two kinds of mongolian properietaries can debase the blood-fat in its degree and reduce the production of lipid perocide. The injury of the inside cortical cell is slight and the scope of pathologic change of artheroscleroisis is reduced and the degree of which is lightened. Conclusions Mongolian proprietaries Ⅱ and Ⅲ have the function of anti- oxidation and can protect the inside cortical cell from injury and inhibit the production of atheroscleroisis.