Aim To study the characteristics of lipid level phenotyping of Shenyang professional populations. Method 3 919 cases (M/F=2 134/1 785, aged 40～89)were enrolled in the study. Lipid levels were classified according to the “recommended guidelines for prevention and treatment of dyslipidemia" of China (1997)and NCEP ATP Ⅲ(2001)of US. Results High prevalence of lipid abnormality was found in Shenyang populations,only 40% had desirable total cholesterol (TC)and triglyceride (TG)level in the group with age above 50. There are 46.7% of the 40～49 aged men and 34.2% 40～49 aged women, 45.1% of the 50～59 aged men and 53.1% 50～59 aged women, 51.1% men above 60 and 63.0% women above 60 who have TC levels above 5.2 mmol/L. And more than 10% of the men have TC levels above 6.2 mmol/L. 18.2% of the 50～59 aged women and 25.8% of the women above 60 also have TC levels above 6.2 mmol/L. Hyperlipoproteinemia high TC was about twice more than high TG. Decreased high density lipoprotein cholesterol (HDLC)was found in 15% male subjects, but only 5% in females. The prevalence of high level HDLC was found in 31.9%～47.3% of female groups, and 16.5%～21.9% in male groups. Conclusion The prevalence of lipid abnormality was more than 50% of the studied subjects above age 50, which means that the atherosclerosis disease risk is high in this population. Lipid modification may be indispensable.