Aim To study how to take advantages of Chinese medicine and western medicine on preventing and cure coronary heart disease;to find an effective way to prevent and cure clinical heart disease with Chinese medicine;Dialectics,entity concept and sythesise adjust and control,traditional Chinese medicine theory combined mordern parmaceutic study and so on are throngh the study. Methods 500 patients after coronary intervention were randomly divided into two groups.One group(n=250) to receive wentongjian which were made from Zhifuzi, shanzha,juemingzi,danshen,shuizhi,huangqi and maimendong.The other group(control group,n=250) to receive routine medical treatment.Changes were observed six months later on total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL),low density lipoprotein(LDL),body mass index(BMI), electrocardiogram(ECG),after the exercise treadmill test(ETT),clinical sympton and whether there was a coronary restenosis or reblocked. Results The blood pressure,TC and TG had no difference(p<0.05) in two groups.HDL,LDL,BMI,fasting blood glucose(FBG) had difference(p<0.05).13 cases in Wentongjian group didn't persist with the 6 months,treatment,14 cases changed into the treatment of traditional Chinese Medicine and 6 cases died in the control group.In Wentongjian group,11 cases feeled nucomfortable after 5 min during treadmill test,but there no changes on electrocardiogram.In control group,46 cases feeled uncomfortable after 5 min during treadmill test,29 cases's S-T sections were evenly lowered and 12 cases S-T sections lowered like slope,five cases have no changes,there were more than 20% restenosis in 16 cases.These were no restenosis or reblocked cases in Wentongjian group.They are significantly better than those in the control group. Conclusions Wentongjian could prevent coronary restenosis and reblocked after percutaneous coronary implantation,adjust the serum lipids metabolism out of disorder.