Aim To analyze the features of the clinical and the coronary angiography in young patients with acute myocardial infarction(AMI)and prevent young people from the earlier occurrence of AMI. Methods 36 young patients(<45 years old) were compared with 40 older patients(>65 years old)from the sex,risk factors,clinical characters,coronary lesion levels,complications and prognosis. Results Most young patients with AMI were men(94.4%). Among them,there were 19(52.8%) patients had hyperlipidemia,26(72.2%)patients had inducement, 33(91.7%)patients had intense chest pains,10(27.7%) patients were interior myocardial infarction and right ventricular infarction,and 31(86.1%) patients had single vessel disease,each of which was higher than the old group.Coronary angiogram revealed that most vessels disease was right coronary atrial,and mainly were single vessel disease,while rarely main coronary artery.These results showed significant difference in the two groups(p<0.01).The complications of young group such as heart failure and pulmonary infection were obviously less than that of the old group(p<0.01). Conclusion The young patients with AMI are mostly man.Most of them,with typical symptom,less complication and good prognosis,had induced factors and risk factors,and most of their vessel diease is single vessel.So an early invasive strategy with percutaneous coronary intervention(PCI) is better for prognosis,and standard secondary prevention can prevent the earlier occurrence of coronary heart disease in young patients.