Aim To explore the relationship of arterial stiffness index(ASI) with carotid artery intima-media thickness(IMT) in hypertensive patients. Methods 124 hypertensive patients who underwent the IMT of carotid arteries were evaluated.They were classified as IMT increased group or no IMT increased group.ASI was measured with YF-1XGYD device.The record of medical history,blood pressure were performed.The biochemical parameters such as blood lipids,glucose and so on were tested. Results There were no significant differences in clinical manifestations between patients of the IMT increased group and no IMT increased group(p<0.05).The ASI value of the IMT increased group was significantly higher than that of the no IMT increased group(p<0.01). Conclusion ASI could be used as an indicator of cardiovascular risk in hypertensive patients.