The Difference of Serum Oxidized Low Density Lipoprotein and High Sensitive C-Reactive Protein Among Different Types of Patients with Coronary Heart Disease
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    Abstract:

    Aim To compare the difference of levels of serum oxidized low density lipoprotein(ox-LDL)and high sensitive C-reactive protein(hs-CRP)among different types of coronary heart disease.Methods Levels of serum ox-LDL and hs-CRP and low density lipoprotein cholesterol(LDLC),total cholesterol(TC)and high density lipoprotein cholesterol(HDLC)were measured among 82 patients with coronary heart disease including 42 acute coronary syndrome(ACS),20 stable angina pectoris(SAP)and 20 old myocardial infarction(OMI)and 22 normal healthy control subjects,then the differencs of levels of all four markers were compared among different types of coronary heart disease.Results Serum ox-LDL levels in the coronary heart disease group(62.5±24.8 μg/L)were significantly higher than that in normal healthy control group(42.3±17.9 μg/L,P<0.05),and serum ox-LDL levels in ACS group(68.9±23.4 μg/L)higher than that in SAP group(41.5±21.3 μg/L)and serum ox-LDL levels in OMI group(50.5±21.6 μg/L,P<0.05);serum hs-CRP levels in coronary heart disease group(15.58±4.32 mg/L)were significantly higher than that in normal healthy control group(6.94±1.93 mg/L,P<0.05),and serum hs-CRP levels in ACS group(19.31±1.43 mg/L)higher than that in SAP group(10.29±1.01 mg/L)and serum hs-CRP levels in OMI group(9.56±1.72 mg/L,P<0.05);serum LDLC levels in coronary heart disease group(3.46±1.11 mmol/L)were significantly higher than that in normal healthy control group(2.87±0.82 mmol/L,P<0.05),and serum LDLC levels in ACS group(3.64±0.85 mmol/L)higher than that in SAP group(3.06±1.23 mmol/L)and serum LDLC levels in OMI group(3.40±1.35 mmol/L,P>0.05).Serum TC/HDLC in the coronary heart disease group(3.46±1.11)were significantly higher than that in normal healthy control group(2.87±0.82).Serum TC/HDLC in different types of patients with coronary heart disease were different(P<0.05).Conclusions The levels of serum ox-LDL and hs-CRP and TC/HDLC have differences among different types of coronary heart disease,and these may be targets of coronary heart disease.

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ZHAO Qing-Xia, LI Hai-Tao, and DIAO Zeng-Li. The Difference of Serum Oxidized Low Density Lipoprotein and High Sensitive C-Reactive Protein Among Different Types of Patients with Coronary Heart Disease[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2008,16(7):559-561.

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  • Received:April 08,2008
  • Revised:July 01,2008
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