Aim To approach the relationship between inflammatory factors and glycosylated hemoglbinA1c(HbA1c) in patients with coronary heart disease(CHD). Methods 203 consecutive patients with CHD was recruited and took oral glucose tolerance test(OGTT).68 cases suffered from diabetes mellitus(DM),80 from impaired glucose homeostasis(IGH) and 55 were with normal glucose.White blood cell(WBC),fibrinogen(FIB),and C-reactive protein(CRP) were compared among the three groups.The relation between WBC,FIB,CRP and HbA1c was analyzed. Results Patients with DM or IGH had a higher level of WBC(P<0.05),FIB(P<0.05) and CRP(P<0.05) compared with the normal glucose.There was statistic positive relation between WBC(R2=0.158 9,P<0.05),CRP(R2=0.228 5,P<0.05),FIB(R2=0.302 4,P<0.05)and HbA1c. Conclusion Patients of CHD with DM and IGT suffer a more severe system inflammation.