Aim To compare the coronary stent implantation between different types of coronary plaque by retrospectively investigating patients who received 64-slice spiral computed tomography coronary angiography before coronary stent implantation. Methods 86 patients who received 64-slice spiral computed tomography angiography before stent implantation from 2007 to 2009 were selected. 137 stents were implanted. Those coronary atherosclerotic plaques were divided into calcified plaque group and noncalcified plaque group based on average computed tomography value of plaque. Clinical character,ballon size,balloon predilation pressure,stent size,stent release pressure in two groups were compared. Results The age of patients in noncalcified plaque group was relatively younger than that in calcified plaque group. The low-density lipoprotein in noncalcified plaque group was higher than that in calcified plaque group. The proportion of 1-vessel disease in noncalcified plaque group was higher than that in calcified plaque group. The size of ballon and stent were similar in those two groups. The balloon predilation pressure in calcified plaque group was higher than that in noncalcified plaque group(898.93±159.67 kPa vs 810.22±112.61 kPa,P><0.01). Stent release pressure in calcified plaque group was higher than that in noncalcified plaque group(1 403.90±273.12 kPa vs 1 243.79±254.12 kPa,P><0.01). Conclusion Compared with noncalcified plaque,calcified plaque was stiffer,and had higher resistance to balloon predilation and stent angioplasty. Identifying the type of plaque before coronary stent implantation was significant.