Apolipoprotein A5 (apoA5) is a new member in the family of apolipoproteins. It is an apolipoprotein with low elasticity and high lipid affinity. In animals and human research,it has been identified as a regulator of triglyceride (TG) metabolism,but the relation between them is unclear. ApoA5 can help maintain the integrity of the droplet,affect very low density lipoprotein (VLDL)-TG serration,increase triglyceride-rich lipoproteins (TRL) clearance in plasma,as well as increase lipoprotein lipase (LPL) and hepatic lipase activity. However,further studies on its functions are needed.