Arterial Stiffness is Associated with Metabolic Syndrome Components in Continuous Ambulatory Peritoneal Dialysis Patients
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    Abstract:

    AimPulse wave velocity (PWV) reflects arterial stiffness and may provide an integrated index of vascular status and cardiovascular disease (CVD) risk. Individual components of the metabolic syndrome(MS) are well-established cardiovascular risk factors.Thus we conducted a cross-sectional study in continuous ambulatory peritoneal dialysis (CAPD) patients to explore the association of MS components with PWV. MethodsPrevalent 148 CAPD patients, were categorized according to the number of traits of the MS into one of three groups (No MS, Risk of MS, MS). Aortic stiffness was assessed by carotid-femoral PWV (C-F PWV). Results C-F PWV was positively associated with age(r=0.427, p<0.01), systolic blood pressure (r=0.444, p<0.01), pulse pressure (r= 0.498, p<0.01), and serum glucose (r=0.366, p<0.01).C-F PWV was negatively associated with serum albumin(r =-0.216, p<0.05).In a multivariate regression analysis, PWV was independently determined by age (p<0.01) and MS score (p=0.01). Adjusted R2 of the model was 0.24. ConclusionMS traits were closely associated with an increased C-F PWV, even after adjustment for confounders. This suggests that commonly recognized MS criteria are also useful when predicting CVD in CAPD patients.

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ZENG Jing, ZHE Xing-Wei, ZHAO Huan-Jia, CHEN Bo-Jun,,WANG Tao. Arterial Stiffness is Associated with Metabolic Syndrome Components in Continuous Ambulatory Peritoneal Dialysis Patients[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2011,19(2):131-134.

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  • Received:December 10,2010
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