Atherosclerosis-related diseases is a complex chronic disease.The exact pathogenesis of the disease is still unclear.So far, chemical drugs used to treat the disease in China are all developed outside China.The scientists worked in Traditional Chinese Medicine take its unique advantages.Under the guidance of TCM basic theory, trial and e-rror, a number of significant achievements have been acquired through clinical practice and drug discovery and development.New drugs which have determined curative effect was created for the prevention and treatment of atherosclerotic disease.They have been recognized and accepted on field of medicine, then go to the world.This article provides an overview of the most representative achievements.