AimTo investigate the relationship between adiponectin and metabolic abnormalities in patients with acute cerebral infarction complicated by metabolic syndrome （MS）.Methods74 hospitalized patients with acute ischemic stroke were studied.All subjects were divided into MS group and non MS group with the criteria of MS published by international diabetes federation (IDF).For patient with MS, we divided it into three MS components group and four or five MS components group.The level of plasma adiponectin and serum TC, TG, LDL, HDL were detected by EILSA technology and the relationship between adiponectin and serum TC,TG, LDL,HDL were examined by Multiple linear regression analysis.ResultsThe patients with acute cerebral infarction complicated by MS showed lower levels of plasma adiponectin and higher levels of serum TG compared with control group (p<0.05).In four or five MS components group, the value of plasma adiponectin decreased obviously compared with control group and the levels of Serum TG, TC, LDL and HDL increased or decreased compared with control group (p<0.05).The result of Multiple linear regression analysis indicated that the levels of plasma adiponectin was significantly associated with TG inversely （b=－1.089，b’=－0.317，p=0.002）.ConclusionsThe value of plasma adiponectin in patients decreased obviously compared with control group.Plasma adiponectin was significantly associated with TG.