Aim To compare the difference in blood pressure control rate between ambulatory blood pressure（ABP） and office blood pressure （OBP） in chronic kidney disease （CKD） patients. Methods We enrolled 225 CKD patients complicated with hypertension in our hospital during 2012.5～2013.2. The general and blood pressure information about these patients were recorded. Results （1） Compared with CKD 1～2 patients, the decline of blood pressure control rate of office systolic blood pressure, 24 h average blood pressure, especially the night time blood pressure in CKD 5 patients were significantly different （P<0.05）. （2）The blood pressure detection rate evaluated by OBP and ABP were different. In CKD 1～2 patients, ambulatory blood pressure detection rate were lower than office blood pressure control rate（79.6% vs 61.3%, P0.038）, however, in CKD 5 patients, the result was on the contrary（83.5% vs 93.0%, P0.029）. Conclusions （1） With the deterioration of renal function, the blood pressure control rate decreases. （2）There are differences between the blood pressure control rate evaluated by two blood pressure measurements in CKD patients of different clinical stage, so it is necessary for CKD patients to take ambulatory blood pressure measurements.