Aim To summarize the clinical manifestation and the characteristic of coronary angiography of patients with the gel-like coronary thrombotic lesions, and to explore the experiences and technique of percutaneous coronary intervention （PCI） for the peculiar coronary lesions. Methods The data was retrospectively analyzed from 6 patients with the gel-like coronary thrombotic lesions. Results Six patients were diagnosed as acute ST-segment elevation myocardial infarction （STEMI）, and the infarction related arteries （IRA） were all right coronary artery. They received selectively PCI one to three weeks after heart attack. Coronary angiography revealed that total occlusion and thrombus occurred in IRA, accompanied with antegrade blood flow of grade TIMI 0. But, the antegrade blood flow in IRA remained the level of grade TIMI 0～1 after guide wires pass through the occlusion. Predilation failed to improve markedly the level of antegrade blood flow, and so did not thrombus aspiration and tirofiban. However, the IRA got antegrade blood flow of grade TIMI 3 after the stent implantation. Conclusion The gel-like coronary thrombotic lesions in IRA results from undissolved and partly fibrotic thrombus after myocardial infarction, and commonly occurs in right coronary artery.