Aim To assess the relationship between brachial-ankle pulse wave velocity （baPWV） and left ventricular diastolic function of hospitalized patients in department of cardiology. Methods 652 patients in department of cardiology were enrolled in the study. The informations of clinical and ultrasonic cardiography were collected. Brachial-ankle pulse wave velocity was measured noninvasively. Results BaPWV increased with the decline of left ventricular diastolic function in four groups and there was statistical significance （P<0.001）. BaPWV was significantly negatively correlated with E/A ratio （r＝－0.257, P<0.001）, and was significantly positively correlated with E/E′ ratio （r＝0.249, P<0.001）. Multiple Logistic regression analysis showed baPWV≥1400 cm/s was a danger factor to left ventricular diastolic disfunction, the RR values were 1.93 （95%CI was 1.09～3.44, P＝0.03）. Conclusions BaPWV is correlated with left ventricular diastolic disfunction, and it can be a screening method for high risk group with left ventricular diastolic disfunction.