Aim To explore the correlation among flowmediated dilatation, nitroglycerinmediated dilatation of brachial artery and intracranial atherosclerotic stenosis in ischemic cerebrovascular disease patients. Methods According to the presence of intracranial vascular stenosis, 67 patients with ischemic cerebrovascular disease are divided into two groups, intracranial vascular stenosis group and control group, of which general data,FMD,NMD are analyzed relatively. Then the relevance of FMD, NMD and the number of intracranial vascular stenosis is further analyzed. Results There are 50 patients in intracranial atherosclerotic stenosis group and 17 patients in control group. Intracranial atherosclerotic stenosis is related to age, FMD, NMD, Hypertension, Diabetes, history of previous stroke/TIA. And there is a negative relationship between FMD （rs－0.869,P0.000＜0.05）,NMD （rs－0.490,P0.000＜0.05） and the number of intracranial vascular stenosis. Unconditional logistic regression analysis shows that FMD can be used as an independent factor of evaluation of intracranial atherosclerotic stenosis, which could be the most likely diagnosis of intracranial vascular stenosis when it was 2.95%. Conclusions FMD was low in patients with intracranial atherosclerotic stenosis，which may also has value in predicting the extent of intracranial vascular stenosis.