Aim To evaluate the association of apolipoprotein B （ApoB） EcoRI polymorphisms with coronary heart disease （CHD） in Chinese population by using a meta-analysis. Methods Hardy-Weinberg equilibrium （HWE） test was used to check genetic equilibrium among genotypes for the selected articles. A fixed or random effect model was selected based on a heterogeneity test. Publication bias was quantified and tested with Begg’s rank correlation method and/or Egger’s linear regression. This meta-analysis was conducted by using Stata 12.0 software. Results Ten reports that met the inclusion criteria were utilized for this meta-analysis. The results of meta-analysis indicated that the pooled OR（95%CI）of E⁺ vs E^-was 1.29 （1.04～1.60）, and P<0.05, the pooled OR（95%CI）of E⁺E⁺ vs E⁺E^- + E^-E^- was 1.28 （1.02～1.61）, and P<0.05. Conclusion In Chinese population, ApoB XbaI locus is an important susceptibility site for CHD.