Aim To study the blood lipid level of Zhengzhou 10636 government staff so as to provide evidence for lipid preventing.Methods According to the standard of 2007 “Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults”, the lipid level of Zhengzhou 10636 government staff was observed in all age groups.Results The level of total cholesterol （TC） was 4.85±0.93 mmol/L, low density lipoprotein cholesterol （LDLC） was 2.92±0.73 mmol/L, high density lipoprotein cholesterol（HDLC） was 1.34±0.28 mmol/L, and the median of triglyceride （TG） was 1.3（0.94～1.89） mmol/L. The total detection rate of dyslipidemia was 29.7%, and hypercholesterolemia, high blood LDLC, low blood HDLC, hypertriglyceridemia detection rates separately were 7.6%, 5.0%, 10.6%, 16.4%. The levels of TC, LDLC and the detection rate of high blood LDLC in male group of the age 30～39, 40～49 were higher than women of the same age（P<0.001）. But after age 50, TC, LDLC levels of the women in each age group increased significantly, and was higher than that of men, and hypercholesterolemia detection rate of women after the age of 50 higher than men（P<0.001）.Conclusions Blood lipid control should be focused on the middle-aged men and postmenopausal women, at the same time to strengthen young people's awareness of dyslipidemia.