Interleukin-8 and Myocardial Infarction

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Interleukin-8 and Myocardial Infarction
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                        MIAO Si-Si1MIAO Si-Si
Department of Cardiology of Chenzhou No.1 Peoples Hospital, Chenzhou, Hunan 423000, China
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GUO Cai-Yan1GUO Cai-Yan
Department of Cardiology of Chenzhou No.1 Peoples Hospital, Chenzhou, Hunan 423000, China
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LI Lu1LI Lu
Department of Cardiology of Chenzhou No.1 Peoples Hospital, Chenzhou, Hunan 423000, China
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and ZHONG Qiao-Qing1,2,3and ZHONG Qiao-Qing
Department of Cardiology of Chenzhou No.1 Peoples Hospital, Chenzhou, Hunan 423000, China;Department of Cardiology of Xiangya Hospital Central China University, Changsha, Hunan 410008, China;Post-doctoral Mobile Stations of Preclinical Medicine in South China University, Hengyang, Hunan 421001, China
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Affiliation:1.Department of Cardiology of Chenzhou No.1 People's Hospital, Chenzhou, Hunan 423000, China;2.Department of Cardiology of Xiangya Hospital Central China University, Changsha, Hunan 410008, China;3.Post-doctoral Mobile Stations of Preclinical Medicine in South China University, Hengyang, Hunan 421001, China)
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Abstract:

Myocardial infarction is a common disease of the cardiovascular system which affects human health seriously. Pathogenesis of myocardial infarction is not fully clarified yet. Currently,interleukin-8 is believed to plays an important role in the development of myocardial infarction. Interleukin-8 not only modulates inflammation,but also stimulates angiogenesis. This review elaborates the progress of research of interleukin-8 in myocardial infarction.

Key words:Interleukin-8; Inflammatory Factors; Angiogenesis; Myocardial Infarction

Reference

[1] Ragino IuI, Kuimov AD, Polonskaia IaV, et al.Dynamics of changes of blood inflammatory-oxidative biomarkers in acute coronary syndrome.Kardiologiia, 2012, 52(2):18-22.

[2] Zorina VN,Belokoneva KP,Bichan NA,et al.The reactants of acute phase of inflammation and anti-inflammatory cytokines under various complications of cardiac infarction .Klin Lab Diaqn, 2012,(1):28-30.

[3] Liang Y, Wang XY, Niu J,et al.Temporal changes and interaction of serum cytokines in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention .Zhonghua Yi Xue Za Zhi,2011, 91(12):819-823.

[4] Li CR,Wang LM,Gong Z,et al.Expression characteristics of neutrophil and mononuclear-phagocyte related genes mrna in the stable angina pectoris and acute myocardial infarction stages of coronary artery disease.J Geriatr Cardiol, 2015, 12(3):279-286.

[5] Velásquez IM, Frumento P, Johansson K, et al .Association of interleukin 8 with myocardial infarction:Results from the Stockholm Heart Epidemiology Program .Int J Cardiol, 2014, 172(1):173-178.

[6] Funayama H,lshikawa SE,Suqawara Y,et al.Myeloperoxidase may contribute to the no-reflow phenomenon in patients with acute myocardial infarction .Int J Cardiol, 2010, 139(2):187-192.

[7] Kirbis S,Breskvar UD,SabovicM, et al.Inflammation markers in patients with coronary artery disease-comparison of intracoronary and systemic levels .Wien Klin Wochenschr, 2010, 122(2):31-34.

[8] Havrylenko TI, Parkhomenko OM, Ryzhkova NO, et al.Cytokines profile of mononuclear leukocytes in patients with myocardial infarction complicated by cardiac insufficiency .Fiziol Zh, 2012, 58(6):23-28.

[9] Novo G,Bellia C,Fiore M,et al.A risk score derived from the analysis of a cluster of 27serum inflammatory cytokines to predicted long term outcome in patients with acute myocardial infarction:a pilot study.Ann Clin Lab Sci, 2015, 45(4):382-390.

[10] De Gennaro L, Brunetti ND, Montrone D, et al .Subacute inflammatory activation in subjects with acute coronary syndrome left ventricular dysfunction .Inflammation, 2012, 35(1):363-370.

[11] Prondzinsky R, Unverzagt S.Interleukin-6、-7、-8 and 10 predict outcome in acute myocardial infarction complicated by cardiogenic shock .Clin Res Cardiol .2012, 101(5):375-384.

[12] Shpektor A.Cardiogenic shock:the role of inflammation.Acute Card Care .2010, 12(4):115-118.

[13] Husebye T, Eritsland J, Amesen H,et al.Association of interleukin 8 and myocardial recovery in patients with ST-elevation myocardial infarction complicated by acute heart failure.PLoS One, 2014, 9(11).

[14] Ganem F, Serrano CV Jr, Fernandes JL ,et al .Preoperative B-type natriuretic peptide, and not the inflammation status, predicts an adverse outcome for patients undergoing heart surgery .Interact Cardiovasc Thorac Surg.2011, 12(5):778-783.

[15] Gigante B,Vikstrom M,Meuzelaar LS,et al.Variants in the coagulation factor 2 receptor(F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels.Thromb Haemost, 2009, 101(5):943-953.

[16] Zhang X, Zhang B, Zhang M,et al .Interleukin-8 gene polymorphism is associated with acute coronary syndrome in the Chinese Han population .Cytokine, 2011, 56(2):188-191.

[17] Libby P,Ridker PM,Hansson GK.Progress and challenges in translating the biology of atherosclerosis.Nature, 2011, 473:317-325.

[18] Rader DJ,Dauqherty A.Translating molecular discoveries into new therapies for atherosclerosis.Nature, 2008, 451:904-913.

[19] Soehnlein O.Multiple roles for neutrophils in atherosclerosis.Circ Res, 2012, 110(6):875-888.

[20] Huber AR, Kunkel SL, Todd RF 3rd, et al.Regulation of transendothelial neutrophil migration by endogenous interleukin-8.Science, 1991, 254(5 028):99-102.

[21] 钟巧青,赵水平,董静,等.高密度脂蛋白对炎症状态下脂肪细胞功能的保护作用.中国药理学通报, 2007, 7:896-898.

[22] 欧志君,常凤军,胡晓侠,等.高胆固醇血症患者高密度脂蛋白损伤血管功能.中国动脉硬化杂志, 2015, 23(12): 1 192-196.

[23] 李华明,欧志君,李艳,等.高密度脂蛋白功能改变可能是动脉粥样硬化形成的危险因素.中国动脉硬化杂志, 2015, 23(12):1 189-191.

[24] Xu J,Chen Q,Shi C,et al.Overexpression of CXCR1/CXCR2 on mesenchymal stromal cells may be an effective treatment for acute myocardial infarction .Cytotherapy, 2009, 11(8): 990-991.

[25] Roberts R,DeMello V,Sobel BE.Deleterious effects of methylprednisolone in patients with myocardial infarction.Circulation, 1976, 53(3 Suppl):1 204-206.

[26] Kempf T, Zarbock A, Vestweber D,et al .Anti-inflammatory mechanisms and therapeutic opportunities in myocardial infarct healing .J Mol Med(Berl).2012, 90:361-369.

[27] 易军.白细胞介素-8对缺血心肌血管新生的影响及其机制研究.长沙:中南大学, 2014； 4-92.

[28] Xie,Sun Z,Chen M,et al.IL-8 up-regulates proliferative angiogenesis in ischemic myocardium in rabbits through phosphorylation of Akt/GSK-3β(ser9) dependent pathways.Int Clin Exp Med, 2015, 8(8):12 498-508.

[29] Zhao X, Zhang W, Xing D,et al.Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction .Am J Physiol Heart Circ Physiol, 2013, 305(4):H590-598.

[30] Kocher AA,Schuster MD,Bonaros N,et al.Myocardial homing and neovascularization by human bone marrow angioblasts is regulated by IL-8/Gro CXC chemokines.J Mol Cell Cardiol, 2006, 40(4):455-64.

[31] Hou Y,Ryu CH,Jun JA,et al.IL-8 enhances the angiogenic potential of human bone marrow mesenchymal stem cells by increasing vascular endothelial growth factor .Cell Biol Int.2014 , 38(9): 1 050-1 059.

[32] Lin YL,Yet SF ,Hsu YT,et al.Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function.Stem Cells Transl Med, 2015, 4(1):44-55.

[33] Maheshwari A, Voitenok NN, Akalovich S, et al.Developmental changes in circulating IL-8/CXCL8isoforms in neonates.Cytokine, 2009, 46(1):12-16.

[34] Gimbrone MA Jr, Obin MS, Brock AF,et al.Endothelial interleukin-8:a novel inhibitor of leukocyte-endothelial interactions.Science, 1989, 246(4 937):1 601-603.

[35] Lefer AM, Johnson G 3rd, Ma XL,et al.Cardioprotective and endothelial protective effects of [Ala-IL8]77 in a rabbit model of myocardial ischaemia and reperfusion.Br J Pharmacol, 1991, 103(1):1 153-159.

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MIAO Si-Si, GUO Cai-Yan, LI Lu, and ZHONG Qiao-Qing. Interleukin-8 and Myocardial Infarction[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2016,24(2):203-206.

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Received:December 28,2015
Revised:January 15,2016
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Online: June 30,2016
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