Aim To evaluate the correlation between left ventricular structure and function parameters and degree of coronary stenosis by using cine magnetic resonance imaging (MRI). Methods 62 cases suspected with coronary heart disease from 2012 to 2013 underwent cine MRI examination to evaluate left ventricular structure and function parameters and degree of coronary stenosis. The stenosis segments of each branch coronary artery were evaluated according to modified Gensini score (GS). All patients were divided into four groups:GS＜5 scores group (10 cases), 5 scores≤GS＜25 scores group (13 cases), 25 scores≤GS＜60 scores group (20 cases) and GS≥60 scores group (19 cases). The correlation was analyzed betwween left ventricular structure and function parameters and GS score. Results The differences of cardiac output (CO) and stroke volume (SV) were not significant among different groups (F＝6.8,5.641, P＞0.05). Left ventricular end systolic volume (LVESV), left ventricular end diastolic volume (LVEDV), left ventricular ejection fraction (LVEF) and myocardial mass (MM) were significantly different among different groups (F＝23.2,1.1,2.5,5.621, P＜0.01). There was no correlation between CO, SV and GS score (P＞0.05). LVEF was negatively correlated with GS score, whereas LVESV, LVEDV, MM were positively correlated with GS score (P＜0.05). The segments deviated from normal values of wall thickness of end systole (WTES), wall thickness of end diastole (WTED), wall thickening % (WT%) and wall motion (WM) were most in the GS≥60 scores group; Deviation segments reduced gradually along with 25 scores≤GS＜60 scores group, 5 scores≤GS＜25 scores group and GS＜5 scores group; The differences were significant among different groups. WTES, WTED, WT% and WM were positively correlated with GS score. Conclusions Left ventricular function becomes worse with the increase of the GS score. Cine MRI can effectively evaluate the myocardial ischemia, and thus, it can help early diagnosis of coronary heart disease.