Aim To estimate the prevalence rate, awareness rate, treatment rate, and control rate of dyslipidemia in Uygur people over 35 years old in Aksu area of Xinjiang. Methods Stratified sampling method was used to select a representative subject of the general population in eight cities of Aksu from April 2012 to June 2014. Results The prevalence rate of dyslipidemia was 53.6%. For women, the prevalence rate of dyslipidemia was higher in older women than that in younger women (53.1% vs. 51.5%, P＝0.024). Among the participants with dyslipidemia, the aware rate, treatment rate, control rate of dyslipidemia were 34.5%, 28.0%, and 16.8%. For the total and 35~54 years old subgroup, the treatment rate of dyslipidemia was significantly higher in women than that in men (for total:30.3% vs. 24.9%, P＝0.004; for 35~54 years subgroup:29.7% vs. 24.2%, P＝0.028). For total subjects, the control rate of dyslipidemia was significantly higher in women than that in men (18.1% vs. 15.0%, P＝0.047). Conclusions Uygur people over 35 years old in Aksu area of Xinjiang have a highly prevalence of dyslipidemia, their awareness rate, treatment rate and control rate of dyslipidemia are low. The treatment rate and control rate of dyslipidemia in men were significantly lower than those in women, we should pay attention to the prevention and treatment of dyslipidemia in men.