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New progress in the study of DES-induced deendothelialization and stent thrombosis
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Cardiovascular Disease Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China)

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R5

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    Abstract:

    Drug eluting stents (DES) have dramatically decreased the rate of in-stent restenosis, which are widely used in patients with atherosclerosis. However, as research continues, increasing evidences have demonstrated that the risk of DES-related stent thrombosis (ST) has tended to increase, which is closely associated with delayed endothelium coverage. Impaired endothelium could induce platelet adhesion and aggregation, incomplete stent apposition, or neoatherosclerosis development. Thus, we will discuss the detailed mechanisms for the DES-related deendothelialization and ST, and the effects of biodegradable stents on vascular endothelium.

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WANG Xin, CUI Yuan-Yuan, ZHAO Fu-Hai. New progress in the study of DES-induced deendothelialization and stent thrombosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2017,25(4):417-421.

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History
  • Received:May 09,2016
  • Revised:November 05,2016
  • Online: May 18,2017
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