Aim To explore the relationship between cumulative triglyceride exposure (cumTG) and ankle-brachial pulse wave velocity(BaPWV). Methods A total of 23499 participants was selected from Kailuan Study stroke cohort, hypertensive population and elderly population cohort to compose observation population, and finally 14662 cases were included in the study cohort. According to cumTG, the research subjects were divided into four groups. The correlation between cumTG and BaPWV was analyzed by partial correlation analysis. Multivariate linear regression and multivariate Logistic regression were used to analyze the effects of cumTG on BaPWV. Results With the increase of cumTG, the average BaPWV level and the detection rate of BaPWV≥ 1400 cm/s showed an increasing trend. The correlation analysis showed that cumTG was positively correlated with BaPWV (r=0.512, P<0.05), and cumTG was positively correlated with BaPWV (r=0.322, P<0.05) after adjustment for age and sex. Multivariate linear regression analysis showed an increase in BaPWV of 4.507 cm/s for each increase in cumTG. Logistic regression analysis showed that the cumTG second quartile, the third quartile, and the fourth quartile were significantly associated with BaPWV≥1400 cm/s compared with the cumTG first quartile after adjustment for other confounders (95%CI) which were 1.667(1.505～1.845), 2.384 (2.111～2.691) and 3.287(2.887～3.741), respectively. Conclusion cumTG is positively correlated with BaPWV.cumTG is a risk factor for the increase of pulse wave velocity.