The adipocytokine omentin and its relationship with atherosclerosis

Home > Archive>Volume 25, Issue 11, 2017 >1179-1183

The adipocytokine omentin and its relationship with atherosclerosis
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                        GAO Li-Jie1,2GAO Li-Jie
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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LI Bin1,2LI Bin
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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SHI Wen-Zhen1,2SHI Wen-Zhen
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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CHEN Xia1,2CHEN Xia
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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HAN Nan-Nan1HAN Nan-Nan
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China
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ZHU Xu-Rong1,2ZHU Xu-Rong
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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WANG Tian-Zhong1,2WANG Tian-Zhong
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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SHI Huan-Huan1,2SHI Huan-Huan
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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ZHAO Ning1,2ZHAO Ning
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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TIAN Ye1,2TIAN Ye
Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China
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Affiliation:1. Neurology Department of Xi’an No.3 Hospital, Xi’an, Shaanxi 710018, China;2.The Medicine Institute of Yan’an University, Yan’an, Shaanxi 716000, China)
Clc Number:R363
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Abstract:

The newly found adipocytokine omentin, secreted from visceral fat tissue, is reported to have close revelation with metabolic syndrome and inflammatory diseases with the ability of improving insulin sensitivity. As an independent indicator of the existence of carotid atherosclerosis plaque, omentin might regulate the incidence and development of atherosclerosis. Omentin may play an anti-atherosclerosis role by protecting endothelia cells from injuries, inhibiting the formation of macrophage-derived foam cells, suppressing the proliferation, migration and the secreting of smooth muscle cells, as well as its anti-inflammatory effects. This review mainly goes through the papers in terms of omentin and its relationship with atherosclerosis, which may provide a valuable view of atherosclerosis.

Key words:Adipocytokine; Omentin; Atherosclerosis

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GAO Li-Jie, LI Bin, SHI Wen-Zhen, CHEN Xia, HAN Nan-Nan, ZHU Xu-Rong, WANG Tian-Zhong, SHI Huan-Huan, ZHAO Ning, TIAN Ye. The adipocytokine omentin and its relationship with atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2017,25(11):1179-1183.

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Received:March 14,2017
Revised:May 18,2017
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Online: November 28,2017
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