Coronary atherosclerotic heart disease and ischemic stroke are the two main diseases of atherosclerotic diseases. They can occur alone or in combination, and are important causes of death and functional deficiency. There are some common risk factors in the two diseases, which are related to the occurrence of the disease. To clarify the correlation between the two diseases is helpful to the prevention and treatment of atherosclerotic diseases, relieving the burden of adverse prognosis and improving the quality of life of the people. At present, many studies have been devoted to exploring the relationship between the two diseases in pathogenesis, disease progression, prognosis and imaging manifestations, among which some results are different. The latest research results are summarized as follows.