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Prognosis of non-valvular atrial fibrillation patients after PCI with hyperhomocysteinemia and low CHA2DS2-VASc in Beijing
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1.Departmemt of Geriatric Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010050, China;2.Departmemt of Heart Center, the Sixth Medical Center of PLA General Hospital, Beijing 100048, China;3.Departmemt of Geriatric Medicine, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia 010010, China)

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R541

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    Abstract:

    Aim To analyse the prognosis of non-valvular atrial fibrillation patients after PCI with hyperhomocysteinemia and CHA2DS2-VASc in Beijing. Methods A total of 1 688 NVAF-PCI patients with CHA2DS2-VASc=0 or 1 was selected to evaluate the risk and influencing factors of major adverse cardiac events (MACE) within 1 year. Patients were divided into two groups according to their plasma homocysteine(Hcy)levels before catheterization:the normal group (1 135 patients, Hcy<15 μmol/L) and the HHcy group (553 patients, Hcy≥15 μmol/L). The primary endpoint was the occurrence of MACE. Results After 1 year of follow-up, HHcy patients had a higher rate of MACE(P=0.017). The main differences between the two groups were ischemic stroke (P=0.009), cardiac death (P=0.046) and non-fatal myocardial infarction (MI)(P=0.044). Conclusion Elevated Hcy levels were independently associated with an increased risk of MACE in non-valvular AF patients with low CHA2DS2-VASc scores after coronary artery stent implantation, and to receive anticoagulant may be effective.

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XIE Xiufeng, LI Tianchang, YAUN Haifeng, ZHANG Boyang, LIU Ruchen, WANG Nannan, LIU Pengfei, HUA Can. Prognosis of non-valvular atrial fibrillation patients after PCI with hyperhomocysteinemia and low CHA2DS2-VASc in Beijing[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2020,28(7):594-598.

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History
  • Received:October 09,2019
  • Revised:November 30,2019
  • Online: June 12,2020
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