After myocardial infarction, there will be a strong inflammatory reaction in the ischemic area, in which a variety of inflammatory cells play a role. Macrophages, as an important component of innate immune response, are very important in the process of tissue repair after myocardial injury. With the development of myocardial infarction, macrophages can differentiate into various subtypes and play a role in phagocytosis of apoptotic cells, angiogenesis, fibrosis and scar maturation. To study the influence of macrophages on myocardial infarction is helpful to explore the improvement of prognosis and diagnosis and treatment of myocardial infarction. This review will focus on the infiltration,polarization and functional changes of macrophages after myocardial infarction.