Research status and progress of animal models of abdominal aortic aneurysm
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Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, China & Department of Cardiovascular Diseases, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China)

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R331;R5

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    Abstract:

    Abdominal aortic aneurysm is a common arterial dilatation disease, with insidious onset and complicated pathogenesis. Due to the lack of early diagnosis and effective intervention measures, the mortality rate of aneurysm is high once ruptured. Therefore, it is urgent to further explore its pathogenesis and find effective treatment measures. Due to many limitations in human trials, it is necessary to replicate animal models for the study of abdominal aortic aneurysms. This article will classify and introduce some classic and innovative animal models according to different research purposes, as well as their respective characteristics and application values, and provide help for researchers to choose appropriate animal model.

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ZHU Junxing, TANG Quanqiao, SHI Xingchi, YI Siyi, ZHOU Can, YANG Ying. Research status and progress of animal models of abdominal aortic aneurysm[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2022,30(6):546-552.

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History
  • Received:May 04,2021
  • Revised:May 20,2021
  • Adopted:
  • Online: May 10,2022
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