mitoNEET:a new target for prevention and treatment of atherosclerosis

Home > Archive>Volume 31, Issue 12, 2023 >1079-1083

mitoNEET:a new target for prevention and treatment of atherosclerosis
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                        GUO Qianqian1GUO Qianqian
Institute of Cardiovascular Disease, University of South China ＆ Key Laboratory for Arteriosclerology of Hunan Province ＆ Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang, Hunan 421001, China
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ZHOU Kaijie2ZHOU Kaijie
Hengyang Medical College of University of South China, Hengyang, Hunan 421001, China
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LEI Jiahua2LEI Jiahua
Hengyang Medical College of University of South China, Hengyang, Hunan 421001, China
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SHI Fuwen2SHI Fuwen
Hengyang Medical College of University of South China, Hengyang, Hunan 421001, China
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PENG Juan1PENG Juan
Institute of Cardiovascular Disease, University of South China ＆ Key Laboratory for Arteriosclerology of Hunan Province ＆ Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang, Hunan 421001, China
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XIONG Wenhao1XIONG Wenhao
Institute of Cardiovascular Disease, University of South China ＆ Key Laboratory for Arteriosclerology of Hunan Province ＆ Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang, Hunan 421001, China
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JIANG Zhisheng1JIANG Zhisheng
Institute of Cardiovascular Disease, University of South China ＆ Key Laboratory for Arteriosclerology of Hunan Province ＆ Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang, Hunan 421001, China
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Affiliation:1.Institute of Cardiovascular Disease, University of South China ＆ Key Laboratory for Arteriosclerology of Hunan Province ＆ Human International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang, Hunan 421001, China;2.Hengyang Medical College of University of South China, Hengyang, Hunan 421001, China)
Clc Number:R541
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Abstract:

This review focuses on the structural characteristics of mitoNEET and its various biological functions as a key protein in regulating mitochondrial function, maintaining cellular iron homeostasis, and participating in energy metabolism. The aim is to provide new intervention methods and therapeutic targets for the prevention and treatment of diseases closely related to inflammation, oxidative stress damage, lipid metabolism disorders, such as obesity diabetes and atherosclerosis-related diseases.

Key words:mitoNEET; mitochondrial function; iron homeostasis; atherosclerosis

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GUO Qianqian, ZHOU Kaijie, LEI Jiahua, SHI Fuwen, PENG Juan, XIONG Wenhao, JIANG Zhisheng. mitoNEET:a new target for prevention and treatment of atherosclerosis[J]. Editorial Office of Chinese Journal of Arteriosclerosis,2023,31(12):1079-1083.

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Received:November 20,2023
Revised:December 01,2023
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Online: December 29,2023
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