This report presents the studies ofsera levels of lipoprotein(a) [Lp (a)] and genetic polymorphism of apolipoprotein(a)[Fapo(a)] in obese children. The aims of this study were to explore the relationship between obese children and high sera levelsof Lp(a) and the distributive characteristics of geneticphenotypes of apo(a).Enzyme-linked immunosorbent assay(ELISA) was used to measure sera levels of Lp(a)in 57 obese children and their parents. The genetic phenotypes of apo (a) were determined by SDS-polyacrylamide gel electrophoresis(SDS-PAGE)and Western blot analysis, Of 75%subjects of obese children with high Lp(a) level, one side of their parents had high concentration of sera Lp(a).A total of 7 different phenotypes of apo(a) were determined from 41 obese children , including 5 different phenotypes of single-isoform and 2 different phenotypes of two-isoform,Obese children mostly had S1 and S2 phenotypes,but the controls generally had S4 phenotype.The similar reports have not been found in the recent5-year references. The study of genetichenotypes of apo(a) in obese children can be of great importance to protection and treatment of the cardiovascular and cerebrovascular disease induced by obesity.