老年2型糖尿病伴冠心病患者冠状动脉病变的临床和影像特点
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The Clinical and Coronary Angiographic Features in Elderly Patients with Type 2 Diabetes Mellitus Combined with Coronary Heart Disease
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    摘要:

    为了观察老年2型糖尿病伴冠心病患者冠状动脉病变的临床和影像学特点,选择133例经冠状动脉造影确诊的冠心病患者,按是否合并2型糖尿病分为两组,进行临床及影像学对照分析,结果发现老年冠心病伴2型糖尿病患者甘油三酯高、高密度脂蛋白胆固醇低、左室射血分数低,冠状动脉病变以3支血管病变及左主干病变多,室壁运动障碍发生率高,但侧枝循环丰富。Logistic回归分析显示年龄、高甘油三酯和低高密度脂蛋白胆固醇为独立危险因素。提示老年2型糖尿病伴冠心病患者冠状动脉病变以3支血管病变及左主干病变为主,高龄、高甘油三酯和低高密度脂蛋白胆固醇对老年冠心病伴2型糖尿病患者的冠状动脉病变程度具有重要作用

    Abstract:

    Aim To evaluate the clinical and coronary angiographic features in elderly patients with type 2 diabetes mellitus combined with coronary heart disease. Methods A total of 133 cases confirmed by coronary angiograph were divided into two groups according to the status if they had combined with type 2 diabetes mellitus or not. Then the study was carried out by case control analysis of the clinical and the data from angiograph. Results High triglyceride, low high density lipoprotein cholesterol and low left ventricular election fraction levels were found in the group of type 2 diabetes mellitus combined with coronary heart disease. Also in this group, the lesions were mainly found in left main coronary artery and all three vessels. The abnormalities of wall motion was more common in this group and the collateral circulation was more abundant than group without typE2 diabetes mellitus. Through Logistic regression analysis, advanced age, high triglyceride and low high density lipoprotein cholesterol levels were confirmed to be independent risk factors. Conclusions In elderly patients with type 2 diabetes mellitus combined with coronary heart disease, the lesions were mainly found in left main coronary artery and all three vessels. Advanced age, high triglyceride and low high density lipoprotein cholesterol levels played an important role in the severity of coronary artery lesions in this kind of patients.

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史扬,范利,吴雪萍.老年2型糖尿病伴冠心病患者冠状动脉病变的临床和影像特点[J].中国动脉硬化杂志,2002,10(2):156~158.

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  • 收稿日期:2001-09-20
  • 最后修改日期:2002-02-25
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