Aim To investigate the role of complex dribbing-pill of danshen pills(DSP) to the calcific vessels and the change of the calcium deposition on the model of vascular calcification in rats.Methods 28 rats were divided into 3 groups rademly: control group(n=9),VitD group(n=10),VitD+DSP group(n=9). VitD group and VitD+DSP group were given by VitD and rats at control group were given the control medicine at the same volume and time.From the fourth day to the ninth week,theVitD+DSP group was given by 15 pills DSP and to the other groups were given by NaCl.At the end of the ninth week,to analyze the role of DSP to the vascular calcification and the effect of calcium deposition,pathological sections with the rats' thoracic aorta were made and calcium in blood,vessels and bones were detected,and so on.Results The model of vascular calcification and osteoporosis with VitD had been succeeded.There were typical calcific nods in vessels.The levels of calcium in vessels in VitD group were obviously higher than those in control group,but the levels of calcium in bones in VitD group were lower than those in control group.DSP can inhibit vascular calcification and transfer the calcium to bones to promote them formation.Significant difference were observed in 3 groups.Conclusion DSP can inhibit vascular calcification availavly and transfer the calcium to bones to promote them formation.