Aim To estimate the influence of percutaneous transluminal renal artery angioplasty(PTRA)in renal hypertension and renal failure by the related factor changes between pre-and post-PTRA.Methods The way of diagnosis of renal artery stenosis and its degrees is radionuclide angiography.The changes of the blood pressure,urea,serum creatinine,β₂ micro-globin,size of kidney,urine examination and renin in pre-and post-PTRA in the 65 patient with unilateral or double renal artery stenosis with totally 75 PTRA were analyzed.Results All of the 75 PTRA were successful.The blood pressure dropped after 24 hours since PTRA and keep steady at the following 3 months.Serum creatinine,creatinine clearance rate,renin dropped after PTRA.Sizes of suffering kidney had no change.And the β₂ micro-globins rised a bit after PTRA.Urine examinations had more positives than that of pre-PTRA.Conclusions PTRA can protect renal function,and it has clinic significance in treatment of hypertension.But it might have side effect in the near future after PTRA.