Aim To discuss carotid intimal-media thickness in children using B-mode ultrasound and look for the risk factors of pre-clinical atherosclerosis.MethodsCarotid intimal-media thickness was detected in seventy-nine children aged from 5 to 17 years old by using B-mode ultrasound.And cardiac structure and function were measured by color Doppler ultrasound.Total plasma cholesterol,triglyceride,high density lipoprotein-cholesterol and low density lipoprotein-cholesterol were detected by HITACHI 7600 automatic biochemical analyzer.Atherogenic index was calculated as LDLC/HDLC.Physical examination was carried on.Blood pressure was measured.Body mass index was calculated according to body height and weight.Familial history of hypertension,coronary heart disease,obesity and dyslipidemia were investigated.The relationship between carotid intimal-media thickness and indexes above was analyzed by Logistic regression.ResultsThere was a difference between the measurements of carotid intimal-media thickness on children with positive and negative histories of obesity,dyslipidemia and hypertension(χ2=4.364,p<0.05).The multiple Logistic regression equation indicated that there were quantitative relationship between carotid intimal-media thickness and diastolic blood pressure and atherogenic index.ConclusionsCarotid intimal-media thickness monitoring should be carried on if children had high risk factors of atherosclerosis for better prevention and intervention.