代谢综合征对脉搏波速度的影响
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Impact of Metabolic Syndrome on Brachial-Ankle Pulse Wave Velocity
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    目的分析某查体人群合并代谢综合征对踝臂脉搏波传导速度的影响。方法某单位健康查体人群,常规体检及测定相关代谢指标,用动脉硬化测定仪测定双侧肢体的踝臂脉搏波传导速度。按中华医学会糖尿病学分会代谢综合征评估标准,确定有无代谢异常并分组,比较各组踝臂脉搏波传导速度的变化特点,分析代谢异常与踝臂脉搏波传导速度的相关性。结果该人群代谢综合征的患病率是13.26%,其中四项代谢异常者占2.43%。随着代谢异常组分和年龄的增加,踝臂脉搏波传导速度逐渐增加,各组间差异有统计学意义(P<0.05),均明显高于对照组,男女各组趋势与总趋势一致。即使单一代谢成分异常,踝臂脉搏波传导速度也显著高于对照组(P<0.05),以单纯高血压组增高最显著。以年龄分为<40岁组,40~59岁组及≥60岁组,前两组均有随着代谢异常数增加,踝臂脉搏波传导速度逐渐增加趋势,≥60岁组此趋势不明显。相关分析可见代谢异常与踝臂脉搏波传导速度存在相关性(左侧r=0.42,P<0.01,右侧r=0.45,P<0.01)。结论踝臂脉搏波传导速度及代谢综合征患病率均随着年龄增加而增加。代谢综合征各组分均是踝臂脉搏波传导速度增加的危险因素,随着代谢异常数的增多,踝臂脉搏波传导速度进一步增加。

    Abstract:

    Aim To analyse the impact of metabolic syndrome(MS) on brachial-ankle pulse wave velocity (BaPWV) in a group of health examination people.Methods The medical examination and blood chemical analysis and related metabolic items were completed in these medical examination people.The brachial-ankle pulse wave velocity (BaPWV) was assessed by using a Form PWV device.Using the standard of MS,defined by the Chinese Diabetes Society in 2004,the people were grouped by the different Metabolic level.The BaPWV were compared among these groups, and the correlation between the BaPWV and the metabolic abnormality was analyse.Results The prevalence of MS was 13.26%,in which the metabolic abnormality in four items was 2.43%.With the increase of abnormal metabolic items and age,the BaPWV increased gradually(P<0.05) and were higher than that of the control group.The same tendency appeared in different sex groups also.Although the single metabolic items were abnormal,compared with the control group,the increase of the BaPWV was significant(P<0.05),especially in the hypertension group.The subjects were also classified into three groups based on the age(<40 years old group,40~59 years old group and>60 years old group).Besides the aged group(>60 years old group),the BaPWV increased with the increasing number of the metabolic abnormality.The correlation between the BaPWV and the metabolic abnormality was significant(left r = 0.42,P<0.01,rightr=0.45,P<0.01).Conclusion The BaPWV and the prevalence of the MS increased with age.All items of the metabolic abnormality were risk factors of the BaPWV increase.The more the metabolic abnormality items were,the more the BaPWV increased.

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刘敏燕,田慧,成晓玲,方福生,邵迎红,卢艳慧,苗新宇,杨彦.代谢综合征对脉搏波速度的影响[J].中国动脉硬化杂志,2009,17(6):477~480.

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  • 收稿日期:2008-12-30
  • 最后修改日期:2009-05-10
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