上海市程桥社区高血压患者空腹血糖受损患病率的调查及相关因素分析
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The Prevalence and Risk Factors for Impaired Fasting Glucose in Shanghai Chengqiao Community with Essential Hypertension
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    目的探讨上海市程桥社区35岁以上原发性高血压患者空腹血糖受损患病率及影响因素。方法选取上海市程桥社区35岁以上居民所有已患原发性高血压患者2596例,其中男1390例,女1206例,年龄35~89岁,平均52.5±12.6岁,进行病史调查,测量血压、体重、身高、腰围、臀围、空腹血糖及血脂等指标,并进行统计学分析。结果在2596例高血压受试者中空腹血糖<5.6mmol/L为1561例,空腹血糖介于5.6~6.9mmol/L为817例,空腹血糖>6.9mmol/L为218例。高血压患者中血糖总异常率达39.9%,其中空腹血糖受损的患病率为31.5%。高血压患者中血糖正常组与空腹血糖受损组的性别构成比、收缩压、体质指数、腰臀比、血糖、总胆固醇及甘油三酯水平差异有统计学意义(P<0.05)。多因素Logistic回归显示,性别(β=0.068,P<0.001)、糖尿病家族史(β=0.468,P<0.05)、总胆固醇(β=0.248,P<0.001)及低密度脂蛋白胆固醇(β=-0.06,P<0.001)与空腹血糖受损有相关性。结论上海市程桥社区35岁以上高血压患者空腹血糖受损患病率高于健康人群,且可能与性别、糖尿病家族史及血脂代谢异常有关。

    Abstract:

    Aim To evaluate the prevalence of impaired fasting glucose (IFG) aged ≥35-year-old in Shanghai Chengqiao Community with essential hypertension and risk factors.Methods 2 596 essential hypertension in Shanghai Chengqiao Community,aged 35~89 years (1 390 males and 1 206 females,mean age 52.5±12.6 years) were recruited in the study.Their medical history,blood pressure,height,weight,waist circumference (WC),hip circumference (HC),fasting plasma glucose (FPG),TC,TG,LDLC,HDLC were detected and analyzed.Results Including 2 596 essential hypertension,there are 1 561 patients whose FPG<5.6 mmol/L and 817 patients whose FPG between 5.6 mmol/L and 6.9 mmol/L.And FPG of 218 patients>6.9 mmol/L.The abnormal rate of FPG in essential hypertension was 39.9% and incidence of IFG was 31.5%.The differences of gender,systolic blood pressure,BMI,waist-to-hip ratio (WHR),TC,TG between the normal glucose group and the IFG group were significant.Multiple factors logistic analysis reveaed gender (β=0.068,P<0.001),family history of diabetes mellitus (β=0.468,P<0.05),TC(β=0.248,P<0.001) and LDLC(β=-0.06,P<0.001) have relationship with IFG.Conclusion The detection rate of IFG is high in hypertension in Shanghai Chengqiao Community and it is related with gender,family history of diabetes mellitus and disorders of lipid metabolism.

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施荣康,王玲琳,应培珍,周青.上海市程桥社区高血压患者空腹血糖受损患病率的调查及相关因素分析[J].中国动脉硬化杂志,2009,17(10):867~870.

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  • 收稿日期:2009-06-05
  • 最后修改日期:2009-10-10
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