Aim To evaluate left ventricular function by the parameter of excursion of left ventricular wall motion in type 2 diabetes mellitus(T2DM) patients. Methods 36 T2DM patients and 25 normal subjects were investigated by real-time three-diametional echocardiography in order to quantitatively analyse the distance and time of the excursion,then the result of the two groups were compared. Results The regional ejection fractior(REF) and the whole ejection fraction(EF) of the two groups were not significantly different(P>0.05).Whole ejection fraction(EF) of the two groups were not significantly different(P>0.05).Compared with control group the standard difference(ESD) and minimum distance(Emin) of the excursion T2DM patients were decreased(P<0.05),and the time of excursion(E%) was increased in T2DM patients group(P<0.05). Conclusions The distance and time of excursion could be helpful for sensitively assessing the early left ventricular dysfunction and myocardiac damage and quantitatively provide accuracy information for clinical preventment and therapy of myocardiac damage in T2DM patients.