新疆汉族30~80岁人群代谢综合征流行病学调查及三种诊断标准的对比研究
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Epidemiological Investigation and Comparison of Three Different Metabolic Syndrome Diagnostic Criteria on Xingjiang Han Population Aged 30 to 80
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    目的通过流行病学调查,了解新疆汉族代谢综合征(MS)患病情况,比较美国国家胆固醇教育计划成年人治疗方案第三次报告(ATPⅢ)、国际糖尿病联盟(IDF)和中华医学会糖尿病学分会(CDS)建议的MS诊断标准在汉族人群中应用的差异。方法对新疆地区2656例汉族30~80岁居民进行横断面调查,根据3种诊断标准分别计算MS患病率,分析不同诊断标准下MS异常组份及危险因素聚集的检出情况,比较3种诊断标准在汉族人群中的一致性。结果3种诊断标准患病率(标化患病率)分别为27.03%(27.18%)、22.40%(20.39%)和16.04%(16.02%)。3种标准对MS患者3个以上危险因素聚集的检出率分别为98.64%、97.9%和92.81%。3种诊断标准在汉人群中应用的一致性两两比较,ATPⅢ标准与IDF标准的一致性较好(一致率为0.9026,Youden指数为0.7928,Kappa值为0.7801),CDS标准与另外两种标准(ATPⅢ和IDF)的一致性不高。结论3种MS诊断标准在新疆汉族人群中应用时,获得的患病率、危险组分聚集情况和一致性差异较大,IDF标准检出率最高,ATPⅢ标准对危险因素聚集检出率最高,且两者一致性较好,优于CDS标准。

    Abstract:

    AimTo investigate the prevalence of metabolic syndrome(MS) among Xingjiang Han population aged 30-80 and compare the differences of three diagnostic criteria used for MS, which are the National Cholesterol Education Program(ATPⅢ),International Diabetes Federation(IDF) and Chinese Medical Association Diabetes Branch(CDS).MethodsA cross-sectional study was conducted on 2656 Xingjiang Han people aged 30-80.The prevalence of MS and the degree of agreement were both calculated according to the three definitions and the results of MS components were also analyzed.ResultsAccording to the three definitions(ATPⅢ,IDF and CDS),The prevalence(adjusted prevalence) of MS were 27.03%(27.18%),22.40%(20.39%) and 16.04%(16.02%).According to the three definitions(ATPⅢ,IDF and CDS),the prevalence of subjects presenteding at least 3 risk factors were 98.64%,97.9% and 92.81%.Among all the MS subjects, the MS diagnostic criteria of ATPⅢand IDF were in good accordance with Kappa index(0.7801),Youden index(0.7928) and concordance rate(0.9026).CDS was in relatively weak agreement when comparing with other definitions (ATPⅢ and IDF).ConclusionOur findings revealed big differences in the prevalence, the degree of agreement and aggregation of risk components on MS among Xingjiang Han population.IDF criteria’s detection rate of MS was the most, ATPⅢ criteria’s detection rate of subjects presenteding at least 3 risk factors was the most,the concordance of ATPⅢ criteria and IDF was better.

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蒋升,杜国利,伊力多斯·阿里什,张莉,严丽君,谢自敬.新疆汉族30~80岁人群代谢综合征流行病学调查及三种诊断标准的对比研究[J].中国动脉硬化杂志,2012,20(2):181~184.

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  • 收稿日期:2011-05-18
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