AimTo explore the correlation between arterial elasticity indexes and serum high sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-9 (MMP-9) in patients with coronary heart disease.MethodsLarge arterial elasticity index (C1) and small arterial elasticity index (C2) were measured with CVProfilor DO-2020.Serum hs-CRP and MMP-9 were measured with ABC-double-antibody sandwich ELISA.ResultsThere was significant difference between coronary heart disease group and control group in C1, C2, MMP-9 and hs-CRP.Logistic regression analysis showed that male, smoking, low density lipoprotein cholesterol, C2, history of hypertension, hs-CRP were independent risk factors for coronary heart disease.Significant inverse correlation was noted between C1 and hs-CRP (r＝－0.51), MMP-9 (r＝－0.49), and between C2 and hs-CRP (r＝－0.69), MMP-9 (r＝－0.55) (all p<0.01) in patients with coronary heart disease.Multiple linear regression analysis showed that independent risk factors for C1 included age, pulse pressure, systolic blood pressure, hs-CRP, low density lipoprotein cholesterol and MMP-9, and independent risk factors for C2 were age, pulse pressure, fasting blood sugar, hs-CRP and low density lipoprotein cholesterol in patients with coronary heart disease.ConclusionsThe present study showed that there was significantly negative correlation between arterial elasticity indexes and serum MMP-9 and hs-CRP in patients with coronary heart disease.The in- flammation may have important impact on arterial elasticity.