心肌梗死经皮冠状动脉介入治疗远期疗效分析
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Long-Term Outcomes of Myocardial Infarction After Coronary Artery Interventional Therapy
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    摘要:

    目的 评价并分析急性心肌梗死不同时间经皮冠状动脉介入治疗(PCI)术后的远期结果。方法 共873例急性ST段抬高型心肌梗死患者接受PCI治疗,除住院期间死亡的11例患者,共随访862例。根据行PCI时间的不同,分为急诊PCI组、补救性PCI组及择期PCI组。随访记录患者出院后死亡、主要心脑血管不良事件及心绞痛情况。Cox回归模型分析各组患者发生不良事件的风险。结果 随访4.26~5.25年(平均随访4.93年),Cox回归分析显示择期PCI组死亡及心衰发生率明显高于急诊PCI组及补救性PCI组(P<0.05);年龄、吸烟、糖尿病、冠状动脉病变数量及左心室射血分数与PCI预后密切相关。结论 年龄、吸烟、糖尿病、冠状动脉病变数量及左心室射血分数多因素参与PCI预后,急性心肌梗死急诊PCI及补救性PCI治疗较择期PCI治疗的远期疗效好。

    Abstract:

    Aim To evaluate the long-term outcomes of myocardial infarction after coronary artery interventional therapy (PCI). Methods 862 patients(mean age 58 years,range 27~82 years) who accepted PCI were followed up. According to the time of PCI, they were divided into three groups: group of emergency PCI, group of remedial PCI and group of elective PCI. Death, major adverse cardiovascular or cerebrovascular events and angina pectoris were observed. The relative risk of adverse events in different patients were analyzed by multivariate Cox analysis. Results The patients were followed up for 4.26 to 5.25 years(average 4.93 years). Incidence rate of death and heart failure in group of elective PCI was higher than the other two groups. Prognosis of PCI was relative with age, smoking, diabetic, coronary artery and ejection fraction. Conclusion Multiple factors participate in the prognosis of PCI, and for the acute myocardial infarction,long-term outcomes of emergency and remedial PCI were better than that of elective PCI.

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谢秀峰,崔晓迎,陈凤英,赵王磊.心肌梗死经皮冠状动脉介入治疗远期疗效分析[J].中国动脉硬化杂志,2013,21(01):69~73.

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  • 收稿日期:2012-03-28
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