AimTo evaluate the diagnostic value of 320-detector row dynamic volume CT angiography (CTA) on patients with coronary artery stenosis.MethodsA total of forty consecutive subjects with suspected coronary heart disease were enrolled in this study.CTA and invasive coronary angiography (ICA) were taken consecutively in order to evaluate the diagnostic value of CTA.The sensitivity, specificity, positive and negative predictive value were calculated with the ICA as the gold standard.ResultsNinety-one and 67 lesions with ≥50% luminal stenosis were detected by CTA and ICA respectively.The sensitivity, specificity, positive and negative predictive value of CTA were 93% (95%CI: 84%～97%), 95% (95%CI: 93%～97%), 74% (95%CI: 6%～82%), 99% (95%CI: 98%～100%) respectively, with the ICA as the gold standard.And the area under the curve (AUC) was 0.98 (0.97～0.99).Conclusions320-detector row dynamic volume CT angiography is reliable in diagnosis of suspected coronary heart disease, which provided a non-invasive method for the diagnosis.