2010~2011年开滦社区人群血脂水平及调脂药物治疗
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Lipids Level and Drug Treatment in Kailuan Community 2010~2011
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    摘要:

    目的 调查开滦社区人群总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、非高密度脂蛋白胆固醇的水平及血脂分层、危险评估、治疗建议、应用调脂药物的流行病学特征,为血脂异常的防治以及进一步预防控制心脑血管疾病的发生提供科学依据。方法 2010年至2011年对开滦社区92967例进行了普查,检测总胆固醇、甘油三酯、低密度脂蛋白胆固醇及高密度脂蛋白胆固醇水平,分析不同性别、年龄段的血脂分层、危险评估、处理建议以及应用调脂药物情况。结果 最终对69488例男性和19228例女性血脂进行统计分析,开滦社区人群血脂水平:总胆固醇男4.93 mmol/L,女5.00 mmol/L;甘油三酯男1.32 mmol/L,女1.17 mmol/L;低密度脂蛋白胆固醇水平男2.58 mmol/L,女2.55 mmol/L;高密度脂蛋白胆固醇男1.51 mmol/L,女1.64 mmol/L;非高密度脂蛋白胆固醇男3.42 mmol/L,女3.36 mmol/L。50~59岁后女性血脂水平高于男性。经年龄、性别标化后,开滦社区人群高总胆固醇、甘油三酯、低密度脂蛋白胆固醇的患病率男性分别为7.48%、20.67%、2.59%,女性分别为9.04%、9.97%、2.88%,低高密度脂蛋白胆固醇的患病率男性11.52%,女性5.80%。11.56%的男性及11.98%的女性建议调脂药物治疗,55~59岁后女性推荐药物治疗的比例超过男性。仅2.28%的男性和2.60%的女性根据指南推荐服用降脂药物。结论 当前开滦社区人群血脂水平较高;根据指南推荐服用调脂药物的比例低;50~59岁后的女性是人群血脂防治的重点。

    Abstract:

    Aim To investigate the plasma total cholesterol (TC),triglyceride (TG),high density lipoprotein cholesterol (HDLC),low density lipoprotein cholesterol (LDLC),and non high density lipoprotein cholesterol (nHDLC) levels,lipid layer,risk assessment,treatment recommendations and drug treatment in Kailuan community and provide data for the prevention and treatment of dyslipidemia,and for further prevention and control of cardiovascular and cerebrovascular diseases. Methods From 2010 to 2011,a total of 92967 cases in the Kailuan community were censured,serum TC,TG,LDLC,HDLC were measured at the central laboratory of Kailuan hospital. Lipid layer,assessment of risks,recommendations and drug treatment were given in different gender and age. Results The study included 69488 men and 19228 women from the Kailuan community. The mean fasting plasma lipids were: TC (male 4.93 mmol/L,female 5.00 mmol/L),LDLC (male 2.58 mmol/L,female 2.55 mmol/L),TG (male 1.32 mmol/L,female 1.17 mmol/L),HDLC (male 1.51 mmol/L,female 1.64 mmol/L) ,nHDLC (male 3.42 mmol/L,female 3.36 mmol/L). Lipids level was higher in female than that of male after the age of 50~59. After adjusted by age and sex,high TC,TG,LDLC prevalence (male 7.48%,20.67%,2.59%,female 9.04%,9.97% and 2.88%) and the prevalence of low HDLC (male 11.52%,female 5.80%) were showed. The proportion of recommended drug treatment was 11.56% in male and 11.98% in female. After the age of 55~59,the proportion of recommended drug treatment were higher in female. In the recommended drug treatment group,only 2.28% male and 2.60% female was taking lipid-lowering drugs. Conclusion Lipids level was high in Kailuan community. According to the guidelines recommend,the proportion of actually taking lipid-lowering drugs was low. The focus group for lipids prevention was female after the age of 55~59.

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金 成,郑晓明,吴云涛,杨新春,张 静,阮春雨,林黎明,赵晓红,吴寿岭.2010~2011年开滦社区人群血脂水平及调脂药物治疗[J].中国动脉硬化杂志,2013,21(10):935~940.

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  • 收稿日期:2013-05-17
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